Longest Range: 2007 Lexus LS460 and 2007 Mercedes-Benz E320 Bluetec

David Axberg
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The Lexus LS460 is a big comfortable car, making it a natural choice for any road trip. It is quiet, it rides softly, and it has acres of space inside. But besides all that, we've chosen it to go on this list of road trip worthy vehicles because of its amazing fuel range. Fully fueled and achieving its estimated 27 mpg on the highway, the big LS should be capable of going 600 miles between gas stations. With that kind of range, one should be able to make it from our office in Ann Arbor to New York City without refueling. And what about the new LS600hL? A hybrid should get even better fuel economy, right? No. Due to its AWD hardware and greater weight, the LS600hL is estimated to reach more like 22 mpg on the highway - bringing its predicted range to a mere 488 miles. Jeez, might as well just stay in town.

Earlier this year, Mercedes-Benz showcased its newest diesel engine by organizing an event from Paris to Beijing in a fleet of Bluetec equipped E-classes. Impressively, the fleet was able to complete the entire journey from France to the capital city of China on just one tank of gas. Okay, that was a lie - they actually had to gas up about every 750 miles, but that statistic is remarkable nevertheless. Diesel engines remain the best choice for those who travel on the highway, with fuel economy that can put many hybrids to shame. In addition, most drivers and passengers wouldn't be able to detect the difference between a Bluetec E-class's refined oil-burner and its gas-engined sibling. Coupled with all the luxury one would expect to find in a Mercedes-Benz, the E320 Bluetec is the perfect companion for crushing continents on your next road trip.

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